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November 2024

Electroenzymatic biosensor for H2 detection

PhD Position 2024-2027 - Marseille, France

Laboratory: Bioenergetics and Protein Engineering (BIP), CNRS, Aix-Marseille University - https://bip.cnrs.fr/groups/bip08/

Position Overview:
Join our dedicated team at the CNRS and Aix-Marseille University to undertake groundbreaking research on hydrogen detection technologies, crucial for sustainable energy solutions. This PhD position offers the opportunity to design and develop a state-of-the-art electroenzymatic biosensor for hydrogen (H2) detection, addressing the urgent need for safe hydrogen storage and utilization.

Research Context:
With the pressing challenge of climate change, the development of CO2-neutral energy sources is vital. Hydrogen is a promising sustainable energy carrier, but its properties require advanced detection systems for safe storage and handling. Our research focuses on the use of Ni-Fe hydrogenase from Aquifex aeolicus for the development of sensitive, miniaturized biosensors capable of detecting hydrogen in various environmental conditions.

Research Goals:
• Optimize enzyme immobilization for enhanced H2 oxidation catalysis.
• Develop methodologies to overcome hydrogen mass transport limitations.
• Employ in situ and operando techniques to map enzyme activity.
• Improve bioelectrode stability under various conditions.
• Explore the effects of biosensor geometry and miniaturization on sensor performance.
• Enhance fundamental understanding of enzymatic behavior in confined spaces and integrate findings with enzymatic fuel cell technologies.

Candidate Profile:
• Master’s degree in Chemistry, with a strong focus on Analytical Chemistry.
• Keen interest in Electrochemistry and 3D Printing.
• Enthusiasm for multidisciplinary research.

Funding: This position is co-funded by Aix Marseille University and the Agence-Innovation-Défense (AID).

Application Process:
Please submit your CV, a motivation letter, copies of academic transcripts and degrees, and two recommendation letters to Dr. Elisabeth Lojou at lojou@imm.cnrs.fr.
Application Deadline: 31st December 2024

Thesis position BIP (PDF)


Bioelectrochemistry
Official Journal of the Bioelectrochemical Society